Micro-Infusion System For Smile Lines
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Micro-Infusion System For Smile Lines
"My makeup kept settling into my smile lines by noon. After 6 weeks with this, the creases are smoother and my foundation stays put. Finally something real!"
- Jenny K.
Verified Buyer
"Didn't think anything could touch my deep smile lines without a needle. Genuinely shocked. The folds are softer and my whole face looks less tired now."
- Lara S.
Verified Buyer
"My esthetician asked what I'd been doing—she thought I got filler somewhere else. Nope. Just this little bottle and five minutes before bed. That's it."
- Tammy G.
Verified Buyer
"I don't know how this works but my smile lines are visibly softer. My daughter said I look 'less stressed.' I'll take it."
- Norma Z.
Verified Buyer
"I hated how my smile lines photographed in harsh lighting. Now they don't cast the same shadow. Sounds vain but it gave me my confidence back."
- Selena K.
Verified Buyer
"My makeup kept settling into my smile lines by noon. After 6 weeks with this, the creases are smoother and my foundation stays put. Finally something real!"
- Jenny K.
Verified Buyer
"Didn't think anything could touch my deep smile lines without a needle. Genuinely shocked. The folds are softer and my whole face looks less tired now."
- Lara S.
Verified Buyer
"My esthetician asked what I'd been doing—she thought I got filler somewhere else. Nope. Just this little bottle and five minutes before bed. That's it."
- Tammy G.
Verified Buyer
"I don't know how this works but my smile lines are visibly softer. My daughter said I look 'less stressed.' I'll take it."
- Norma Z.
Verified Buyer
"I hated how my smile lines photographed in harsh lighting. Now they don't cast the same shadow. Sounds vain but it gave me my confidence back."
- Selena K.
Verified Buyer
(419 Reviews) | 80,000+ Happy Customers
Micro-Infusion System For Smile Lines
PDRN + Copper Peptide + NAD⁺
Order Today – Get it by New Year's
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Free shipping
120 days guarantee
DERM Approved
🧴Prevents Contamination & Infection Risk
💧Fresh Heads = Deeper Serum Penetration
⚡Accelerates Results vs. Dull Heads
🎯Designed for Periorbital & Nasolabial Areas
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Real Results. Clinical Science.
See What's Possible
Feel The Difference After Your First Sessions
Clinical research shows that the right actives can start visibly improving fold depth and texture within weeks. With Botanique Paris® Micro-Infusion, users typically notice softer-looking smile lines, improved skin texture around the mouth, and more resilient-feeling skin—without the downtime, bruising, or cost of filler appointments. Your existing skin immediately begins receiving targeted actives, and your nasolabial area will look smoother, firmer, and more refined with each twice-weekly session.
Why Surface Creams Can't Fix Smile Lines
Traditional anti-aging creams sit on top of your skin, never reaching the layers where fold depth and texture issues become visible. Botanique Paris® Micro-Infusion works differently—precision 0.25mm delivery creates temporary micro-channels that help 30 clinically-studied actives reach beyond the surface barrier.
The result? PDRN + GHK-Cu + NAD⁺ work where they're actually needed—not sitting on top hoping to absorb. This is why users see visible fold softening that creams simply can't deliver.
Drug-free. No fillers. Just targeted delivery that actually reaches the problem.
What Makes Botanique Paris®
The Ultimate Micro-Infusion System
Copper Tripeptide-1
The Matrix Reset Signal
- Modulates 4,000+ genes; resets aged fibroblast expression toward youthful profiles.
- Supports dermal density and collagen gene expression where folds form.
Copper Tripeptide-1
Clinical Evidence
The Matrix Reset Signal
What it does: GHK-Cu resets aged fibroblast genetics toward youthful patterns. It upregulates collagen/elastin synthesis, downregulates inflammatory genes, and modulates 4,000+ human genes—essentially "reprogramming" skin cells to behave younger.
✓ Broad Institute study confirmed GHK-Cu influences 4,000+ genes (31.2% of genome), upregulating collagen, antioxidant, and DNA repair genes while downregulating pro-aging pathways. pmc.ncbi.nlm.nih
✓ Clinical study (N=21, 3 months) showed 28-51% increase in subdermal collagen/elastin density via ultrasound imaging. eurekalert.org
PDRN (Sodium DNA)
The Renewal Coordinator
- DNA-derived polynucleotide studied in wound-healing; activates A2A receptors for tissue regeneration.
- Stimulates fibroblast activity; clinical studies show accelerated dermal remodeling.
PDRN (Sodium DNA)
Clinical Evidence
The Renewal Coordinator
What it does: PDRN activates adenosine A2A receptors to signal tissue repair, reduce inflammation, and stimulate fibroblast proliferation—accelerating the skin's natural renewal process.
✓ Systematic review (34 studies, 25 years) confirmed PDRN promotes tissue regeneration via A2A receptor activation with excellent safety. pubmed.ncbi.nlm.nih
✓ RCT (N=216, 8 weeks) showed PDRN doubled healing rate and reduced median healing time from 49 to 30 days. pubmed.ncbi.nlm.nih
NAD⁺
The Cellular Power Plant
- Central cofactor for ATP synthesis, DNA repair, and sirtuin activation.
- Powers ATP-dependent collagen synthesis machinery; declines 50% from age 20–50.
NAD⁺
Clinical Evidence
The Cellular Power Plant
What it does: NAD⁺ is the central energy cofactor for ATP synthesis, DNA repair, and sirtuin activation. Age-related NAD⁺ decline (50% by middle age) is a key driver of visible aging—without it, cells cannot execute collagen synthesis even with perfect genetic signals.
✓ Cell Metabolism research confirmed NAD⁺ declines to ~50% by middle age, driving metabolic dysfunction and age-related degeneration. pmc.ncbi.nlm.nih
✓ Annual Review study showed NAD⁺ supplementation improves metabolism and protects against age-related decline. pubmed.ncbi.nlm.nih
Palmitoyl Tripeptide-38
The Fold-Depth Architect
- Signals synthesis of 6 major ECM constituents: Collagen I, III, IV, fibronectin, HA, laminin-5.
- 97% of participants showed wrinkle improvement in 4-week clinical trial.
Palmitoyl Tripeptide-38
Clinical Evidence
The Fold-Depth Architect
What it does: Stimulates 6 major ECM components simultaneously (Collagen I, III, IV, fibronectin, HA, laminin-5) for comprehensive fold depth reduction across multiple dermal layers.
✓ Clinical trial (N=35, 56 days) showed 71% wrinkle improvement and 8-9% skin roughness reduction. pmc.ncbi.nlm.nih
✓ In vitro studies confirmed stimulation of all six ECM constituents with increased dermal density. scirp.org
Acetyl Tetrapeptide-2
The Firmness Restorer
- Supports skin elasticity and firmness; helps skin bounce back after facial movement.
- Works synergistically with collagen-builders to maintain structural resilience.
Acetyl Tetrapeptide-2
Clinical Evidence
The Firmness Restorer
What it does: Increases skin firmness and elasticity by remodeling actin cytoskeleton in keratinocytes, helping skin "spring back" rather than permanently crease in high-movement areas.
✓ AFM study demonstrated dose-dependent increase in keratinocyte stiffness via actin remodeling. pmc.ncbi.nlm.nih
✓ Peptide review confirmed Ac-Tet-2 role in elasticity via cytoskeleton remodeling. journals.sagepub.com
Bifida Ferment Lysate
The Texture Refiner
- Probiotic-derived active that strengthens skin barrier and smooths surface texture.
- Calms micro-inflammation; prevents makeup from settling into creases.
Bifida Ferment Lysate
Clinical Evidence
The Texture Refiner
What it does: Postbiotic that upregulates barrier genes (filaggrin, loricrin, involucrin) while reducing inflammatory cytokines—creating optimal renewal conditions and preventing inflammation-accelerated fold formation.
✓ In vitro study (J Cosmet Dermatol) showed upregulation of barrier genes + decreased inflammatory markers (IL-8, TNF-α). pubmed.ncbi.nlm.nih
✓ RCT (N=66, 2 months) demonstrated significant barrier resistance increase and reduced skin sensitivity. pubmed.ncbi.nlm.nih
Adenosine
The Wrinkle Relaxer
- Boosts cellular energy (ATP precursor); clinically shown to reduce wrinkle depth.
- Smooths expression lines; supports skin's natural repair during rest.
Adenosine
Clinical Evidence
The Wrinkle Relaxer
What it does: ATP precursor that energizes fibroblasts and activates receptors to increase collagen production and provide immediate wrinkle-smoothing. Korea's MFDS approved adenosine ≥0.04% as functional wrinkle ingredient.
✓ RCT (N=126, 8 weeks) showed significant periorbital smoothness improvement at 3 weeks by optical profilometry. pubmed.ncbi.nlm.nih
✓ Clinical study (N=22, 10 weeks) demonstrated wrinkle depth reduction and improved dermal density. pubmed.ncbi.nlm.nih
Niacinamide
The Tone Equalizer
- Improves uneven skin tone and texture around the perioral area.
- Strengthens skin barrier; supports overall skin resilience with consistent use.
Niacinamide
Clinical Evidence
The Tone Equalizer
What it does: Multifunctional active that inhibits melanosome transfer (reduces melanin-related shadows), strengthens barrier via ceramide synthesis, and reduces inflammation for smoother, more even perioral tone.
✓ RCT (N=202, 10 weeks) showed significant hyperpigmentation reduction vs. placebo. pubmed.ncbi.nlm.nih
✓ Clinical trial (N=18, 8 weeks) demonstrated 35-68% melanosome transfer inhibition. Pubmed.ncbi.nlm.nih
The Only Micro-Infusion System Your Smile Lines Need
Surface serums can't reach fold depth. Fillers plump temporarily but don't rebuild. Botanique Paris® delivers 30 clinically-backed actives directly where nasolabial folds form—via painless 0.25mm precision stamping.
Beyond the 8 hero ingredients above, our serum includes Sodium Hyaluronate, Allantoin, Beta-Glucan, and Acetyl Hexapeptide-8 to amplify hydration, comfort, and remodeling.
Smooth Your Smile Lines…
And Your Wallet Too!
Whilst nasolabial fillers can cost upwards of ~$1,500 per session and leave you with swelling and tenderness that can last up to two weeks, our 5-minute treatment gives you professional-grade dermal-delivery technology and visible smoothing results, without the injections.
For 1/10th the price, here's what you get:
- Visible fold softening in just weeks—no bruising, no downtime
- Clinically-backed ingredients that support visible renewal without repeat appointments
- 6 months of visible renewal for less than one filler session
Skip the expensive procedures and achieve smoother, firmer smile lines from home today.
Erase Signs of Aging
In Just A Few Minutes Per Session
For Best Results: We recommend using the Micro-Infusion System 2 times
per week, so that the serum's active ingredients can support visible fold softening between sessions!
STEP 1
Twist off the needle head and pour 0.5 mL of serum into the applicator using the dropper, then secure back on. Clean and dry the nasolabial fold area on both sides of the face.
STEP 2
Stamp along each fold: ~25 light stamps per side (50 total), or adjust based on your fold length and comfort level. Use 25–50% overlap between stamps. Keep the device flat and use light, even pressure—no dragging.
STEP 3
Pour any remaining serum onto fingertips and massage along the fold area (or entire face). Let absorb—no rinsing for 8–12 hours (4 hours minimum). Avoid acids/retinoids for 24–48 hours. Stay consistent: expect visible smoothing within 4–8 weeks.
Here's Why Women Love
Botanique Paris® Micro-Infusion System
It Targets Fold Depth At The Source
Unlike surface serums that can't reach where folds form, our formula delivers matrix-rebuilding actives directly to the dermal layer—addressing depth, texture, and firmness simultaneously.
30x Better Penetration Than Topicals
Our precision micro-infusion technology bypasses the skin barrier that blocks traditional serums—ensuring every drop of our 30-ingredient formula reaches where it matters.
Real Results In Just 4–8 Weeks
Feel the difference with softer folds and smoother texture within weeks—no more waiting months to see if your anti-aging serum works.
Professional Results, Without The Injections
Get filler-level smoothing without bruising, swelling, or $1,500 appointments. Just 5 minutes, twice a week, from home.
Real Doses, Real Science
Every active is dosed at clinically-studied concentrations—PDRN, NAD⁺, Copper Peptide, and matrix-renewal peptides working together, not just label decoration.
No Fillers, No Repeat Appointments
Say goodbye to injections that metabolize in months—our clean formula supports lasting renewal that compounds with every session.
Softer, Smoother Smile Lines in 120 Days Or Your Money Back
Didn't see the fold smoothing you hoped for? You have 120 days to get a full refund—no questions asked.
Frequently Asked
Questions
YOU GOT QUESTIONS. WE GOT ANSWERS
What are the ingredients in the serum?
Core Regenerative Trio
- Copper Tripeptide-1 (GHK-Cu): Your anchor peptide for visible matrix renewal and fold-depth softening, especially effective when delivered via micro-infusion.
- PDRN (Sodium DNA): A polynucleotide that supports the skin's natural renewal process and post-stamp comfort.
- NAD⁺ (Nicotinamide Adenine Dinucleotide): A cellular cofactor that supports skin energy, repair, and renewal at the mitochondrial level.
Matrix Renewal Peptides
- Palmitoyl Tripeptide-38: Signals multiple ECM constituents (collagens I/III/IV, laminin, fibronectin) for smoother, firmer fold contour.
- Acetyl Tetrapeptide-2: Firmness and elasticity peptide that supports dermal architecture in high-movement zones like smile lines.
Targeted Peptide Complexes
- HALOXYL® Complex (N-Hydroxysuccinimide + Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7 + Chrysin): Targets the look of shadows and discoloration via heme-byproduct clearance plus periorbital ECM support.
- Eyeseryl® (Acetyl Tetrapeptide-5): The de-puffing peptide that helps reduce the appearance of fluid retention and morning puffiness.
Brightening + Barrier Duo
- Niacinamide: Evidence-backed barrier reinforcement, tone correction, and sebum balance.
- N-Acetyl Glucosamine (NAG): Upstream tone perfecter that synergizes with niacinamide for even, luminous skin.
Barrier & Texture Support
- Bifida Ferment Lysate: Postbiotic that upregulates barrier genes and helps calm visible redness from repeated stamping.
- Sodium Heparin (Heparan-Sulfate Analog): Replenishes a key ECM scaffold for barrier feel and fine-line appearance.
Wrinkle Softeners & Circulation Support
- Adenosine: Wrinkle-appearance softener that helps smooth expression lines and support skin recovery.
- Caffeine: Micro-circulation support that supports microcirculation and skin firmness.
Advanced Antioxidant Defense
- Ergothioneine: A rare, ultra-stable antioxidant that protects cells from oxidative stress at the deepest level.
- Carnosine: Dipeptide that fights glycation and supports skin elasticity, resilience, and long-term firmness.
Hydration & Comfort System
- Sodium Hyaluronate (High Molecular Weight): Forms a moisture-locking barrier on the skin surface for lasting hydration.
- Sodium Hyaluronate (Low Molecular Weight): Penetrates deeper to plump and hydrate from within.
- Saccharide Isomerate: Binds to skin for long-lasting, natural hydration that doesn't wash off.
- Glyceryl Glucoside: Supports natural moisture channels for enhanced hydration and skin resilience.
- Betaine: Balances and soothes the skin while maintaining optimal hydration under stress.
- Beta-Glucan: Accelerates visible remodeling and calms micro-inflammation post-treatment.
- Allantoin: Soothes and conditions skin post-stamp for faster recovery and comfort.
- Panthenol (Pro-Vitamin B5): Conditions, hydrates, and supports skin recovery and softness.
- Ectoin: Extremophile-derived stress protector that shields skin from environmental and oxidative damage.
Vehicle & Delivery System
- Aqua (Water): Purified water base.
- Glycerin: Humectant that draws moisture to the skin for lasting hydration.
- Propanediol: Lightweight, skin-friendly solvent that enhances active delivery.
- Pentylene Glycol: Hydrating solvent with mild antimicrobial properties.
- Polyquaternium-51: A skin-mimicking, breathable film former that helps actives stay in place while keeping skin comfortable.
Preservative & Stability System
- Phenoxyethanol: Broad-spectrum preservative to keep the formula fresh and safe.
- Ethylhexylglycerin: Preservative booster and skin-conditioning agent.
- Citric Acid: pH adjuster for optimal formula stability and skin compatibility.
No added fragrance. No silicones. Drug-free. Designed for micro-infusion and consistent at-home use.
How does it actually work?
Botanique Paris® combines precision micro-infusion technology with a multi-active serum built around PDRN, NAD⁺, copper peptides, and matrix-renewal peptides.
The 0.25mm needles create temporary micro-channels that allow the serum to bypass the stratum corneum (the barrier that blocks over 95 percent of traditional topicals) and reach the dermal layer where nasolabial folds (smile lines) actually form.
This improves absorption by up to 30x compared to surface application, supports collagen and elastin renewal pathways, and creates a healthier dermal environment—all in a professional-grade, at-home routine.
How quickly will I see results?
Most users notice early improvements within 3–4 weeks of consistent use. The first changes are typically smoother texture, softer fold edges, and more hydrated-looking skin around the NLF (nasolabial fold) area.
More significant fold-depth softening and firmness improvements typically build over 6–12 weeks, depending on your starting point and consistency. Skin renewal is gradual—progress photos every 4 weeks help you see changes your eyes get used to daily.
Is it painful to use?
Most users describe the sensation as a mild tingling or light pressure—more like a firm facial massage than a "needle" feeling. Our 0.25mm precision needles are designed to stimulate the dermal layer without drawing blood or causing significant discomfort.
You may notice slight pinkness or warmth for 30–60 minutes after treatment—this is completely normal and indicates the micro-channels are active. If you have sensitive skin, start with lighter pressure and fewer stamps, then build up as your skin adjusts.
How often should I use it?
We recommend twice per week, with at least 2–3 rest days between sessions to allow your skin to complete its natural renewal cycle.
- Week 1: Start with one session to test comfort and skin response.
- Week 2+: Move to twice weekly (e.g., Monday and Thursday, or Tuesday and Saturday).
Consistency matters more than frequency. Twice weekly for 12 weeks will outperform sporadic daily use.
What's the needle depth?
Our NLF (nasolabial fold) system uses precision 0.25mm needles. This depth reaches the upper dermis where collagen remodeling signals are most active—without causing bleeding, bruising, or requiring clinical downtime.
Once your skin is tolerant (typically after 4–6 weeks), you may progress to 0.30–0.35mm for enhanced penetration in deeper folds. We include guidance on when and how to advance.
Is there any downtime?
Virtually none. You may experience mild pinkness or a "flushed" appearance for 30–60 minutes post-treatment—similar to a brisk walk or light facial. This fades quickly and can be covered with mineral makeup if needed.
The micro-channels close within approximately 30–60 minutes. Most users perform their treatment in the evening and wake up with no visible evidence of the session.
Can I use it if I've had dermal fillers?
Yes, but with timing considerations:
- Before fillers: You can use the Micro-Infusion System right up until your filler appointment. Some users find that pre-treating the area improves skin quality and filler integration.
- After fillers: Wait at least 2–4 weeks after injectable fillers before resuming micro-infusion in the treated area. This allows the filler to fully settle and reduces any risk of displacement.
If you're unsure, consult your injector. Many aesthetic practitioners now recommend micro-infusion between filler appointments to extend results and improve skin quality.
Is it safe for all skin types?
Yes. The Botanique Paris® Micro-Infusion System is designed for all Fitzpatrick skin types (I–VI) and works across a range of skin concerns—from early fine lines to established nasolabial folds (smile lines).
Our serum is fragrance-free, silicone-free, and formulated without harsh penetration enhancers that can trigger sensitivity. The postbiotic and barrier-support actives (Bifida Ferment Lysate, Allantoin, Beta-Glucan, Ectoin) are specifically included to keep skin calm between sessions.
Note: Avoid use on broken, infected, or actively inflamed skin. If you have a history of keloid scarring or are currently using prescription retinoids, consult your dermatologist before starting.
Will Botanique Paris® Micro-Infusion Serum, with so many actives, overwhelm my skin or cause irritation?
Not at all. While the Botanique Paris® NLF (Nasolabial Fold) Micro-Infusion Serum features over 25 actives and co-actives (excluding water), they're selected and balanced for perfect synergy—not overload.
Most actives are gentle peptides, hydrators, and skin-calming agents, formulated at clinically-researched concentrations with supportive ingredients that reinforce comfort, barrier strength, and tolerance. Plus, soothing co-actives like Ectoin, Beta-Glucan, Panthenol, Allantoin, and Bifida Ferment Lysate are included specifically to buffer and help prevent irritation.
For most users—even those with sensitivity—this means you benefit from deep, multi-layered renewal without risk of "doing too much." As always, start gradually and follow provided usage guidance, but this serum is formulated for consistent, visible results with minimal risk of irritation or overwhelm.
What should I avoid or be cautious about after applying Botanique Paris® NLF Micro-Infusion Serum?
To ensure optimal results and protect your skin, please follow these post-application guidelines:
- Do not touch or rub the treated area. Gentle tapping is all that's needed—rubbing can cause irritation or disrupt micro-channels.
- Avoid applying other strong actives (such as retinol, exfoliating acids, or benzoyl peroxide) to the nasolabial area for at least 48 hours. Combining too many powerful ingredients may lead to irritation.
- Wait at least 4 hours before applying makeup, sunscreen, or other products on the treated skin—ideally overnight. This gives skin time to reseal and absorb all actives.
- Do not use on broken, sunburned, or infected skin. Wait until the area is fully healed before resuming.
- Do not wash the area or get it wet for at least 4 hours. Water can dilute the formula and disrupt the actives' penetration.
- Avoid waxing, threading, or in-office treatments (like chemical peels or lasers) on the NLF area for at least 7 days after use.
- Minimize direct sun exposure immediately after application, and always use sunscreen the next morning—newly treated skin can be extra vulnerable.
- Do not use more than recommended. Overuse may not improve results and may increase risk of redness, stinging, or sensitivity.
- Discontinue if you notice persistent stinging, itching, swelling, or rash, and consult a healthcare provider if symptoms worsen.
Summary: Gentle handling, minimal product layering, sun protection, and patience with the renewal process are key for the best, safest results. When in doubt, follow the included usage guide or reach out to our support team.
Can I use my own serums with the device?
We strongly recommend using only the Botanique Paris® serum with our micro-infusion system.
Here's why: not all serums are formulated for transdermal delivery. Many contain fragrances, essential oils, preservatives, or pH levels that can cause irritation or adverse reactions when delivered past the skin barrier.
Our serum is specifically engineered for micro-infusion—with a pH-balanced, irritant-free formula and actives dosed for dermal delivery, not surface application.
Is there a money-back guarantee?
Yes. We offer a 120-day money-back guarantee on all Micro-Infusion System purchases.
If you don't see the fold-smoothing results you hoped for after consistent use, simply contact us within 120 days for a full refund—no questions, no hassle. We only win when you see real results.
How is this different from derma-rolling?
Three key differences:
- Precision vs. drag: Derma-rollers drag across the skin at inconsistent angles, creating uneven micro-tears. Our stamping mechanism delivers perpendicular, controlled penetration at a consistent depth—less trauma, better channels.
- Integrated delivery: Rollers are separate from your serum. You roll, then apply, and hope absorption happens. Our system combines the micro-infusion device with a purpose-built serum, ensuring actives enter the channels while they're open.
- Targeted application: Rollers cover broad areas indiscriminately. Our precision head lets you target the nasolabial fold (smile line) specifically—right where the serum needs to go.
Think of it as the difference between a scattershot and a precision instrument.
Are the needle heads reusable?
Yes, with proper care. You can reuse a cartridge if you sanitize it after each session:
- Rinse the head under warm water to remove serum residue.
- Soak in 70 percent isopropyl alcohol for 10 minutes.
- Air-dry with needles facing up.
For optimal performance, we recommend replacing the head after approximately 5–8 uses. Needles gradually dull with use, and sharper needles create cleaner channels with less drag.
Pro tip: Mark each cartridge with a small dot after each use to track your count. If you ever notice bent needles, increased discomfort, or visible wear, replace immediately.
Is it easy to use?
Absolutely. The system is designed to be intuitive:
- Twist off the needle head, add 0.5mL of serum with the dropper, secure back on.
- Clean and dry your face.
- Stamp along each nasolabial fold (~25 stamps per side, adjust to your fold size and comfort).
- Massage any remaining serum into the area.
- Let absorb—no rinsing for 8–12 hours.
Most users master the technique in their first session. Each kit includes detailed instructions, and our support team is available if you need guidance.
How much of an area does one treatment cover?
Each 0.5mL session is calibrated specifically for bilateral NLF (nasolabial fold) treatment—both smile lines, from nose to mouth corners, plus the surrounding marionette area if desired.
If you're treating additional areas (forehead, glabella, etc.), you may need additional serum. Our multi-bottle bundles are designed for users who want to address multiple facial zones.
Who should use the Micro-Infusion System?
The NLF (Nasolabial Fold) Micro-Infusion System is ideal for:
- Adults noticing early smile lines who want to slow progression
- Those with established nasolabial folds seeking non-injectable improvement
- Post-filler users who want to extend results between appointments
- Anyone who wants professional-grade delivery without clinic visits
- People who've tried topical anti-aging products without meaningful results
Not recommended for: Those with active acne, rosacea flares, eczema, or open wounds in the treatment area; those currently on Accutane; those with a history of keloid scarring (consult your dermatologist first).
Will I lose my results if I stop using it?
After 3–4 months of consistent use, many users see meaningful fold softening and improved skin quality that persists for some time after stopping.
However, skin biology is ongoing. If you completely stop any skincare routine, your skin will gradually return toward its baseline over months. Most users find that switching to a lighter maintenance schedule (once weekly, or a few times per month) helps preserve results without the full twice-weekly commitment.
I've tried everything. Why would this be different?
Most anti-aging products fail for one reason: they never actually reach the dermis.
The stratum corneum (your skin's outer barrier) blocks over 95 percent of topically applied actives. You can have the best ingredients in the world, but if they're sitting on the surface, they're not doing much.
Botanique Paris® solves the delivery problem:
- 0.25mm micro-infusion creates temporary channels that guide actives directly to the dermal layer—bypassing the barrier that blocks ordinary serums.
- Multi-pathway formulation addresses fold depth, matrix renewal, firmness, and barrier health simultaneously—not just one mechanism.
- Clinically-dosed actives at levels that match published research, not trace amounts for label decoration.
It's not magic. It's better delivery plus smarter formulation—built for people who are done hoping their expensive cream will finally absorb.
What makes Botanique Paris® different from other devices?
Most brands sell you a device and a generic serum separately—you become the formulator, hoping they work together.
Botanique Paris® was engineered as a complete system:
- Delivery + formula, built together. The 0.25mm precision head is designed specifically for our serum's viscosity and active profile.
- 13 hero actives, not 1 token ingredient. PDRN, NAD⁺, GHK-Cu, Palmitoyl Tripeptide-38, Acetyl Tetrapeptide-2, Ergothioneine, Carnosine, and more—each targeting a different pathway in fold formation and skin renewal.
- Recovery built in. Bifida Ferment Lysate, Allantoin, Ectoin, and Beta-Glucan keep skin comfortable enough to maintain a consistent twice-weekly routine.
One system. One serum. One job: deliver what your smile lines actually need, where they actually need it.